PRISM identifies eligible patients, exposes what threatens participation, and governs progression through completion.Most systems optimize who enters the funnel. PRISM determines whether participation can hold.Readiness becomes an operating signal before preventable failure becomes rescue.
If recruitment were the constraint, predictability would have improved with it. It has not. Claims-based targeting, digital outreach at scale, AI-driven patient matching, faster funnel speed. The industry solved reach. It did not solve durability. Screen failure remains 20-40%. Early withdrawal is routine. Rescue recruitment is a line item.
More recruitment does not fix behavioral friction. Enrollment is a decision. Retention follows that decision. No system before PRISM operationalizes readiness at scale.
The only study recruitment, enrollment, and retention operating system that is backed by readiness throughout the study lifecycle.
PRISM governs a lifecycle, not a funnel. Every stage is a decision point: readiness assessed, developed, or validated before a patient advances. No skipped stages. No patients pushed forward because a quota demands it.
PRISM evaluates every patient who engages, groups them by shared friction patterns, then applies readiness strategies that build participation.
PRISM also works upstream: it can identify optimal sites based on real-world data signals and inform protocol design by surfacing readiness barriers before a study launches. When readiness intelligence shapes the protocol itself, friction is engineered out before a single patient is enrolled.
One predicts what is likely to break the trial. The other keeps it from breaking.
Eligibility first. Then readiness.
Step 1 filters your population for medical eligibility against the protocol. Step 2 maps behavioral and social friction for eligible patients, surfacing whether they will actually enroll and complete.
De-identified medical and pharmacy claims. Your protocol and I/E criteria. Site list and NPI-level HCP rosters. Census-based SDOH overlays and behavioral overlays.
Engage. Educate. Prescreen. Hand off.
We engage the eligible patients, educate them on the trial, walk them through prescreening, and hand each one to your sites with a per-patient readiness report so the site team knows exactly who is coming and what support they need.
Patient engagement and trial education. Guided prescreening. Warm handoff to sites with a readiness handoff for each patient. Real-time reporting to sponsor and sites.
Intelligence tells you what is about to break. Orchestration keeps it from breaking.
Most patient experience solutions focus on materials. PRISM focuses on execution stability. Six principles govern how readiness is built, sustained, and protected through completion.
Prepares patients to evaluate participation in the context of their daily life, not just protocol details.
Surfaces time, procedures, logistics, and disruption early, reducing regret and misalignment after enrollment.
Reinforces understanding as burden and uncertainty accumulate, when static education typically fails.
Engages caregivers as feasibility partners and decision influencers, not passive observers.
Structures information to match how people process complex decisions, reducing cognitive overload and false confidence.
Addresses fear, uncertainty, and anxiety before they undermine trust and commitment.
Most trial metrics report post-failure. PRISM surfaces live signals that enable intervention before recovery becomes impossible.
Together, these indices provide real-time visibility into execution health. They surface instability while recovery is still possible.
PRISM is an AI-enabled Patient Readiness Operating System. It evaluates patient profiles, assesses readiness, builds readiness through targeted interventions, governs advancement, and sustains participation from recruitment through completion. Six stages. One system.
Recruitment vendors optimize lead generation. Engagement platforms count activity. PRISM governs whether patients will complete, using readiness thresholds instead of volume targets, measuring capacity instead of clicks.
PRISM paces unready patients but accelerates overall execution by preventing screen failures, dropout, and rescue recruitment. Result: stable enrollment curves and faster completion. Speed without readiness wastes resources.
No. PRISM removes preventable readiness and retention burden upstream. Sites receive prepared patients with validated context, cutting re-explanation, rescheduling, and no-shows.
Three live execution indices. PXCI measures experience stability. IEQS measures engagement integrity. CRI measures recruitment predictability. Together they surface instability while recovery is still possible.
CORE is a trial execution system for patient readiness education. PRISM is a full operating system: education plus readiness intelligence and governed advancement. CORE can stand alone or surface within PRISM's AI-driven flows.
Proprietary constructs defined by Jumo Health. Each one is a measurable operational concept, not a marketing term. View all definitions →
What sponsors recover when readiness is governed across the lifecycle.
Patients arrive pre-qualified by both medical eligibility and readiness, not chosen by funnel volume.
Activation governed by completion probability, so enrollment curves stop being rescue projects.
Readiness decay detected mid-trial and met with friction-specific intervention before dropout.
Each compounds with the next. Better screening reduces rescue. Better retention protects timelines. Both protect NPV.
Powering studies for 17 of the world's top 25 pharmaceutical companies.
Why This Works Now
Jumo Health is a Patient Experience Organization (PXO). Where the industry has long focused on recruitment and eligibility, we address a deeper, more persistent challenge: whether patients are truly prepared to participate and remain engaged once the realities of a clinical trial begin. Built on artificial intelligence, real-world data, social determinants of health, behavioral science, and human-centered design.
Conservative math on a 300-patient Phase 3 study. The hidden multiplier is bigger than the direct loss.
60 patients lost early. 300-patient Phase 3, 20% early withdrawal at $40K conservative per-patient cost.
Rescue recruitment. Site rework and coordinator time. Timeline compression. Reforecasting and milestone risk. NPV erosion.
10% improvement preserves 30 patients at $40K each, before reduced rescue cost and timeline savings.
Even a 5-10% lift in completion probability is the largest single recoverable line item left in the trial budget.
In two days, you get three execution diagnostics on your program.
How likely each eligible patient cluster is to activate, persist, and complete, before any intervention.
The barriers most likely to suppress activation, enrollment, and completion in each cluster, and how to mitigate them.
Which clusters to target, which barriers to address, which interventions to deploy, and what completion lift to expect.